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Losartan Potassium 124750-99-8 Losartan Potassium 124750-99-8

Losartan Potassium 124750-99-8
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Maklumat asas Losartan Potassium 124750-99-8

Name

Losartan Potassium

Molecular Formula

C22H23ClKN6O

Molecular Weight

462.01

Quality Standard

USP

Package Size

25kg/drum

Brief Introduction

Losartan is an angiotensin II receptor antagonist drug used mainly to treat high
blood pressure (hypertension). It was the first angiotensin II antagonist to be marketed.
Losartan potassium is marketed by Merck & Co. Inc. under the trade name Cozaar,
and is available in generic form.

Penggunaan Losartan Losartan Potassium 124750-99-8

  • Terutamanya digunakan untuk merawat tekanan darah tinggi.

COA Losartan Losartan Potassium 124750-99-8

ITEMS

SPECIFICATION

RESULTS

APPEARANCE

A WHITE TO OFF-WHITE POWDER.


WHITE CRYSTALLINE POWDER

IDENTIFICATION

(1) INFRARED ABSORPTION

MUST SIMILAR TO REFERENCE STANDARD

CONFORMS


(2) ULTRAVIOLET ABSORPTION

MUST SIMILAR TO REFERENCE STANDARD


CONFORMS

3)TEST FOR POTASSIUM MUST BE POSITIVE

POSITIVE

WATER

NOT MORE THAN 0.5%

0.2%

HEAVY METALS

NOT MORE THAN 0.001%

CONFORMS

CHROMATOGRAPHIC PURITY

ANY INDIVIDUAL IMPURITY:NMT 0.2%

0.02%

TOTAL IMPURTIES:NMT 0.5%

0.10%

RESIDUAL SOLVENTS

CYCLOHEXANE

ISOPROPANOL  ALCOHOL


NMT 0.1%

NMT 0.2%


0.010%

0.03%

ASSAY (HPLC)

98.5%-101.0%

99.4%

ADDITIONAL ITEMS


PARTICLE SIZE

90% LESS THAN 38 MICRONS

29.8 MICRONS

CONCLUSION

COMPLIES WITH USP32 AND REQUIREMENT OF ADDITIONAL ITMES.


MORE_DETAIL Losartan Potassium 124750-99-8

Maklumat asas Losartan Potassium 124750-99-8

Name

Losartan Potassium

Molecular Formula

C22H23ClKN6O

Molecular Weight

462.01

Quality Standard

USP

Package Size

25kg/drum

Brief Introduction

Losartan is an angiotensin II receptor antagonist drug used mainly to treat high
blood pressure (hypertension). It was the first angiotensin II antagonist to be marketed.
Losartan potassium is marketed by Merck & Co. Inc. under the trade name Cozaar,
and is available in generic form.

Penggunaan Losartan Losartan Potassium 124750-99-8

  • Terutamanya digunakan untuk merawat tekanan darah tinggi.

COA Losartan Losartan Potassium 124750-99-8

ITEMS

SPECIFICATION

RESULTS

APPEARANCE

A WHITE TO OFF-WHITE POWDER.


WHITE CRYSTALLINE POWDER

IDENTIFICATION

(1) INFRARED ABSORPTION

MUST SIMILAR TO REFERENCE STANDARD

CONFORMS


(2) ULTRAVIOLET ABSORPTION

MUST SIMILAR TO REFERENCE STANDARD


CONFORMS

3)TEST FOR POTASSIUM MUST BE POSITIVE

POSITIVE

WATER

NOT MORE THAN 0.5%

0.2%

HEAVY METALS

NOT MORE THAN 0.001%

CONFORMS

CHROMATOGRAPHIC PURITY

ANY INDIVIDUAL IMPURITY:NMT 0.2%

0.02%

TOTAL IMPURTIES:NMT 0.5%

0.10%

RESIDUAL SOLVENTS

CYCLOHEXANE

ISOPROPANOL  ALCOHOL


NMT 0.1%

NMT 0.2%


0.010%

0.03%

ASSAY (HPLC)

98.5%-101.0%

99.4%

ADDITIONAL ITEMS


PARTICLE SIZE

90% LESS THAN 38 MICRONS

29.8 MICRONS

CONCLUSION

COMPLIES WITH USP32 AND REQUIREMENT OF ADDITIONAL ITMES.

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